COPA antibody (AA 550-650)

Catalog No. ABIN7266424

This Rabbit Polyclonal antibody specifically detects COPA in WB. It exhibits reactivity toward Human.

Quick Overview for COPA antibody (AA 550-650) (ABIN7266424)

Target: COPA (Coatomer Protein Complex, Subunit alpha (COPA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COPA Antibody

Binding Specificity: AA 550-650

Purpose: COPA Rabbit pAb

Sequence: FIYTTSNHIK YAVTTGDHGI IRTLDLPIYV TRVKGNNVYC LDRECRPRVL TIDPTEFKFK LALINRKYDE VLHMVRNAKL VGQSIIAYLQ KKGYPEVALH F

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 550-650 of human COPA (NP_001091868.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COPA

Target: COPA (Coatomer Protein Complex, Subunit alpha (COPA))

Alternative Name: COPA

Background: In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.,COPA,AILJK,HEP-COP,Signal Transduction,COPA

Gene ID: 1314

UniProt: P53621

Pathways: Hormone Activity