This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
CIRBP
(Cold Inducible RNA Binding Protein (CIRBP))
Alternative Name
CIRBP
Background
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity. Promotes assembly of stress granules (SGs, when overexpressed.,CIRBP, CIRP, cold-inducible RNA-binding protein,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Cell Cycle,CIRBP