COMMD5 antibody (AA 1-224)

Catalog No. ABIN7266471

This anti-COMMD5 antibody is a Rabbit Polyclonal antibody detecting COMMD5 in WB and IF. Suitable for Human.

Quick Overview for COMMD5 antibody (AA 1-224) (ABIN7266471)

Target: COMMD5 (COMM Domain Containing 5 (COMMD5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMMD5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-COMMD5 Antibody

Binding Specificity: AA 1-224

Purpose: COMMD5 Rabbit pAb

Sequence: MSAVGAATPY LHHPGDSHSG RVSFLGAQLP PEVAAMARLL GDLDRSTFRK LLKFVVSSLQ GEDCREAVQR LGVSANLPEE QLGALLAGMH TLLQQALRLP PTSLKPDTFR DQLQELCIPQ DLVGDLASVV FGSQRPLLDS VAQQQGAWLP HVADFRWRVD VAISTSALAR SLQPSVLMQL KLSDGSAYRF EVPTAKFQEL RYSVALVLKE MADLEKRCER RLQD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human COMMD5 (NP_054785.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COMMD5

Target: COMMD5 (COMM Domain Containing 5 (COMMD5))

Alternative Name: COMMD5

Background: May modulate activity of cullin-RING E3 ubiquitin ligase (CRL complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity. Down-regulates activation of NF-kappa-B.,COMMD5,HCARG,HT002,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,COMMD5

Molecular Weight: 24kDa

Gene ID: 28991

UniProt: Q9GZQ3