DGCR8 antibody

Catalog No. ABIN7266760

This Rabbit Monoclonal antibody specifically detects DGCR8 in WB. It exhibits reactivity toward Human.

Quick Overview for DGCR8 antibody (ABIN7266760)

Target: DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DGCR8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DGCR8 Antibody

Purpose: DGCR8 Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human DGCR8

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DGCR8

Target: DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Alternative Name: DGCR8

Background: This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],C22orf12, DGCRK6, Gy1, pasha,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,DGCR8

Molecular Weight: 100kDa

Gene ID: 54487

UniProt: Q8WYQ5

Pathways: Regulatory RNA Pathways