DPYSL2 antibody

Catalog No. ABIN7266770

The Rabbit Monoclonal anti-DPYSL2 antibody has been validated for WB and IF. It is suitable to detect DPYSL2 in samples from Human.

Quick Overview for DPYSL2 antibody (ABIN7266770)

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DPYSL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-DPYSL2 Antibody

Purpose: CRMP2/DPYSL2 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human CRMP2/DPYSL2

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DPYSL2

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Alternative Name: DPYSL2

Background: This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2,Cell Biology & Developmental Biology,Cytoskeleton_Microtubules,Neurodegenerative Diseases,Neurodegenerative Diseases_Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neuroscience,Protein phosphorylation,DPYSL2

Molecular Weight: 62kDa

Gene ID: 1808

UniProt: Q16555

Pathways: Regulation of Cell Size