DPYSL2 antibody (AA 400-500)

Catalog No. ABIN7266769

Product Details anti-DPYSL2 Antibody

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Binding Specificity: AA 400-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPYSL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: [KO Validated] CRMP2/DPYSL2 Rabbit pAb

Sequence: RIAVGSDADL VIWDPDSVKT ISAKTHNSSL EYNIFEGMEC RGSPLVVISQ GKIVLEDGTL HVTEGSGRYI PRKPFPDFVY KRIKARSRLA ELRGVPRGLY D

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Grade: KO Validated

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human CRMP2/CRMP2/DPYSL2 (NP_001377.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DPYSL2

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Alternative Name: DPYSL2 (DPYSL2 Products)

Synonyms: CRMP-2 antibody, CRMP2 antibody, DHPRP2 antibody, DRP-2 antibody, DRP2 antibody, N2A3 antibody, ULIP-2 antibody, ULIP2 antibody, TOAD-64 antibody, crmp2 antibody, dhprp2 antibody, drp-2 antibody, drp2 antibody, unc-33 antibody, unc33 antibody, dpysl2 antibody, CRMP 2 antibody, PCRMP 2 antibody, PCRMP-2 antibody, PCRMP2 antibody, PfCRMP 2 antibody, PfCRMP-2 antibody, AI851130 antibody, Crmp2 antibody, Musunc33 antibody, Ulip2 antibody, CRMP2A antibody, dihydropyrimidinase like 2 antibody, dihydropyrimidinase-like 2 antibody, dihydropyrimidinase like 2 L homeolog antibody, dihydropyrimidinase-like 2b antibody, cysteine repeat modular protein 2, putative antibody, DPYSL2 antibody, dpysl2.L antibody, dpysl2b antibody, PfCRMP2 antibody, dpysl2 antibody, Dpysl2 antibody

Background: This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,DPYSL2,CRMP-2,CRMP2,DHPRP2,DRP-2,DRP2,N2A3,ULIP-2,ULIP2,Cell Biology & Developmental Biology,Microtubules,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,DPYSL2

Molecular Weight: 58kDa/62kDa

Gene ID: 1808

UniProt: Q16555

Pathways: Regulation of Cell Size