Dysferlin antibody

Catalog No. ABIN7266868

This Rabbit Monoclonal antibody specifically detects Dysferlin in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Dysferlin antibody (ABIN7266868)

Target: Dysferlin (DYSF)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Dysferlin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Dysferlin Antibody

Purpose: Dysferlin (Romeo) Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Dysferlin (Romeo)

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Dysferlin

Target: Dysferlin (DYSF)

Alternative Name: DYSF

Background: The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008],FER1L1, LGMD2B, MMD1,Cell Biology & Developmental Biology,DYSF

Molecular Weight: 280kDa

Gene ID: 8291

UniProt: O75923