E3 SUMO-Protein Ligase PIAS3 (LOC101740849) antibody

Catalog No. ABIN7266879

This anti- antibody is a Rabbit Monoclonal antibody detecting in WB and IHC. Suitable for Human.

Quick Overview for E3 SUMO-Protein Ligase PIAS3 (LOC101740849) antibody (ABIN7266879)

Target: E3 SUMO-Protein Ligase PIAS3 (LOC101740849)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details

Purpose: PIAS1+PIAS2 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human PIAS1+PIAS2

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: E3 SUMO-Protein Ligase PIAS3 (LOC101740849)

Alternative Name: PIAS1/PIAS2

Background: This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],DDXBP1, GBP, GU/RH-II, ZMIZ3,PIAS1/PIAS2

Molecular Weight: 76kDa

Gene ID: 8554, 9063

UniProt: O75925, O75928