Ensa antibody (AA 1-100)

Catalog No. ABIN7266947

The Rabbit Polyclonal anti-Ensa antibody has been validated for WB. It is suitable to detect Ensa in samples from Human.

Quick Overview for Ensa antibody (AA 1-100) (ABIN7266947)

Target: Ensa (ENSA) (Endosulfine alpha (ENSA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ensa antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Ensa Antibody

Binding Specificity: AA 1-100

Purpose: ENSA Rabbit pAb

Sequence: MAGGLGCDVC YWFVEDTQEK EGILPERAEE AKLKAKYPSL GQKPGGSDFL MKRLQKGQKY FDSGDYNMAK AKMKNKQLPS AGPDKNLVTG DHIPTPQDLP

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ENSA (NP_996929.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Ensa

Target: Ensa (ENSA) (Endosulfine alpha (ENSA))

Alternative Name: ENSA

Background: The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.,ENSA,ARPP-19e,Neuroscience,ENSA

Molecular Weight: 11kDa/12kDa/13kDa/14kDa/15kDa

Gene ID: 2029

UniProt: O43768