ERLIN1 antibody (AA 259-348)

Catalog No. ABIN7267005

This anti-ERLIN1 antibody is a Rabbit Polyclonal antibody detecting ERLIN1 in WB and IHC. Suitable for Human.

Quick Overview for ERLIN1 antibody (AA 259-348) (ABIN7267005)

Target: ERLIN1 (ER Lipid Raft Associated 1 (ERLIN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERLIN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ERLIN1 Antibody

Binding Specificity: AA 259-348

Purpose: ERLIN1 Rabbit pAb

Sequence: KADAEYYAAH KYATSNKHKL TPEYLELKKY QAIASNSKIY FGSNIPNMFV DSSCALKYSD IRTGRESSLP SKEALEPSGE NVIQNKESTG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 259-348 of human ERLIN1 (NP_006450.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ERLIN1

Target: ERLIN1 (ER Lipid Raft Associated 1 (ERLIN1))

Alternative Name: ERLIN1

Background: The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.,ERLIN1,C10orf69,Erlin-1,KE04,KEO4,SPFH1,SPG62,erlin-1,ERLIN1

Molecular Weight: 38kDa

Gene ID: 10613

UniProt: O75477