XPO1 antibody

Catalog No. ABIN7267067

The Rabbit Monoclonal anti-XPO1 antibody is suitable to detect XPO1 in samples from Human. It has been validated for WB, IHC and IF.

Quick Overview for XPO1 antibody (ABIN7267067)

Target: XPO1 (Exportin 1 (XPO1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This XPO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-XPO1 Antibody

Purpose: CRM1/XPO1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human CRM1/XPO1.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for XPO1

Target: XPO1 (Exportin 1 (XPO1))

Alternative Name: XPO1

Background: This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015],CRM1,emb,exp1,XPO1,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,XPO1

Molecular Weight: 110kDa

Gene ID: 7514

UniProt: O14980

Pathways: M Phase