Fascin antibody

Catalog No. ABIN7267142

The Rabbit Monoclonal anti-Fascin antibody has been validated for WB and IHC. It is suitable to detect Fascin in samples from Human.

Quick Overview for Fascin antibody (ABIN7267142)

Target: Fascin (FSCN1)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Fascin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Fascin Antibody

Purpose: Fascin/FSCN1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Fascin/FSCN1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Fascin

Target: Fascin (FSCN1)

Alternative Name: FSCN1

Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],FAN1, HSN, SNL, p55,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,Cytoskeleton_Microfilaments,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,FSCN1

Molecular Weight: 54kDa

Gene ID: 6624

UniProt: Q16658