Fatty Acid Synthase antibody

Catalog No. ABIN7267157

The Rabbit Monoclonal anti-Fatty Acid Synthase antibody is suitable to detect Fatty Acid Synthase in samples from Human. It has been validated for WB, IHC, IP and IF.

Quick Overview for Fatty Acid Synthase antibody (ABIN7267157)

Target: Fatty Acid Synthase (FASN)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-Fatty Acid Synthase Antibody

Purpose: Fatty Acid Synthase (FASN) Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human FASN

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: FASN

Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008],FAS,OA-519,SDR27X1,FASN,AMPK Signaling Pathway,Cancer,Cardiovascular,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Lipid Metabolism,Lipids,Lipids_Fatty Acids,Neuroscience,RNA Binding,Signal Transduction,Tumor biomarkers,FASN

Molecular Weight: 273kDa

Gene ID: 2194

UniProt: P49327

Pathways: AMPK Signaling