FNDC4 antibody (AA 45-167)

Catalog No. ABIN7267196

The Rabbit Polyclonal anti-FNDC4 antibody is suitable to detect FNDC4 in samples from Human. It has been validated for WB.

Quick Overview for FNDC4 antibody (AA 45-167) (ABIN7267196)

Target: FNDC4 (Fibronectin Type III Domain Containing 4 (FNDC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNDC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FNDC4 Antibody

Binding Specificity: AA 45-167

Purpose: FNDC4 Rabbit pAb

Sequence: DRPPSPVNVT VTHLRANSAT VSWDVPEGNI VIGYSISQQR QNGPGQRVIR EVNTTTRACA LWGLAEDSDY TVQVRSIGLR GESPPGPRVH FRTLKGSDRL PSNSSSPGDI TVEGLDGERP LQT

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 45-167 of human FNDC4 (NP_073734.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FNDC4

Target: FNDC4 (Fibronectin Type III Domain Containing 4 (FNDC4))

Alternative Name: FNDC4

Background: Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.,FNDC4,FRCP1,Cell Biology & Developmental Biology,FNDC4

Molecular Weight: 25kDa

Gene ID: 64838

UniProt: Q9H6D8