FBLIM1 antibody (AA 180-272)

Catalog No. ABIN7267208

The Rabbit Polyclonal anti-FBLIM1 antibody has been validated for WB. It is suitable to detect FBLIM1 in samples from Human.

Quick Overview for FBLIM1 antibody (AA 180-272) (ABIN7267208)

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBLIM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBLIM1 Antibody

Binding Specificity: AA 180-272

Purpose: FBLIM1 Rabbit pAb

Sequence: TDICAFCHKT VSPRELAVEA MKRQYHAQCF TCRTCRRQLA GQSFYQKDGR PLCEPCYQDT LERCGKCGEV VRDHIIRALG QAFHPSCFTC VTC

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-272 of human FBLIM1 (NP_060026.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FBLIM1

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Alternative Name: FBLIM1

Background: This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.,FBLIM1,CAL,FBLP-1,FBLP1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Extracellular Matrix,FBLIM1

Molecular Weight: 30kDa/40kDa

Gene ID: 54751

UniProt: Q8WUP2