FBLIM1 antibody (C-Term)

Catalog No. ABIN952270

This Rabbit Polyclonal antibody specifically detects FBLIM1 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for FBLIM1 antibody (C-Term) (ABIN952270)

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBLIM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-FBLIM1 Antibody

Binding Specificity: AA 301-331, C-Term

Specificity: This antibody recognizes Human FBLIM1 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 301-331 amino acids from the C-terminal region of Human FBLIM1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FBLIM1

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Alternative Name: FBLIM1

Background: This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.Synonyms: FBLP-1, FBLP1, Filamin-binding LIM protein 1, MIG2-interacting protein, Migfilin, Mitogen-inducible 2-interacting protein

Molecular Weight: 40670 Da

Gene ID: 54751

NCBI Accession: NP_001019386