GABRD antibody (AA 330-430)
Quick Overview for GABRD antibody (AA 330-430) (ABIN7267323)
Target
See all GABRD AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 330-430
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Purpose
- GABRD Rabbit pAb
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Sequence
- FAHFNADYRK KQKAKVKVSR PRAEMDVRNA IVLFSLSAAG VTQELAISRR QRRVPGNLMG SYRSVGVETG ETKKEGAARS GGQGGIRARL RPIDADTIDI Y
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 330-430 of human GABRD (NP_000806.2).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- GABRD (GABA A Receptor delta (GABRD))
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Alternative Name
- GABRD
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Background
- Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.,GABRD,EIG10,EJM7,GEFSP5,Neuroscience,GABRD
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Molecular Weight
- 50kDa
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Gene ID
- 2563
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UniProt
- O14764
Target
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