GABRD antibody (N-Term)

Catalog No. ABIN2792262

The Rabbit Polyclonal anti-GABRD antibody (ABIN2792262) specifically detects GABRD in WB and IHC. The antibody is reactive with Human, Rat, Mouse, Dog, Cow and Rabbit samples.

Quick Overview for GABRD antibody (N-Term) (ABIN2792262)

Target: GABRD (GABA A Receptor delta (GABRD))

Reactivity: Human, Rat, Mouse, Dog, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GABRD Antibody

Binding Specificity: N-Term

Purpose: GABRD Antibody - N-terminal region

Sequence: MDAPARLLAP LLLLCAQQLR GTRAMNDIGD YVGSNLEISW LPNLDGLIAG

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%

Characteristics: This is a rabbit polyclonal antibody against GABRD. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GABRD

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABRD

Target: GABRD (GABA A Receptor delta (GABRD))

Alternative Name: GABRD

Background:

Targeted Subunit: delta

Background Information: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. The GABRD gene encodes the delta subunit.Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit.

Gene Name: Gamma-aminobutyric acid (GABA) A receptor, delta

Alternative Symbols: EJM7, EIG10, GEFSP5

Protein Name: Gamma-aminobutyric acid receptor subunit delta

Molecular Weight: 51kDa

Gene ID: 2563

NCBI Accession: NP_000806

UniProt: O14764