GABARAPL2 antibody

Catalog No. ABIN7267326

This anti-GABARAPL2 antibody is a Rabbit Monoclonal antibody detecting GABARAPL2 in WB. Suitable for Human.

Quick Overview for GABARAPL2 antibody (ABIN7267326)

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GABARAPL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABARAPL2 Antibody

Purpose: GABARAPL2 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human GABARAPL2

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GABARAPL2

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Alternative Name: GABARAPL2

Background: Ubiquitin-like modifier involved in intra-Golgi traffic (By similarity. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation (By similarity. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.,ATG8, ATG8C, GATE-16, GATE16, GEF-2, GEF2,Autophagy,Autophagy_Regulator,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Signal Transduction,GABARAPL2

Molecular Weight: 14kDa

Gene ID: 11345

UniProt: P60520

Pathways: Autophagy