Gephyrin antibody
Quick Overview for Gephyrin antibody (ABIN7267375)
Target
See all Gephyrin (GPHN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Gephyrin Rabbit mAb
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human Gephyrin
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Gephyrin (GPHN)
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Alternative Name
- GPHN
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Background
- This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008],GEPH, GPH, GPHRYN, HKPX1, MOCODC,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton_Microtubules,Neuroscience,GPHN
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Molecular Weight
- 93kDa
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Gene ID
- 10243
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UniProt
- Q9NQX3
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Pathways
- Synaptic Membrane, Skeletal Muscle Fiber Development
Target
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