Gephyrin antibody

Catalog No. ABIN7238975

Product Details anti-Gephyrin Antibody

Target: Gephyrin (GPHN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gephyrin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human GPHN

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Gephyrin

Target: Gephyrin (GPHN)

Alternative Name: Gphn (GPHN Products)

Synonyms: 5730552E08Rik antibody, AI662856 antibody, BC027112 antibody, C230040D23 antibody, GPH antibody, GPHRYN antibody, geph antibody, Geph antibody, GPHN antibody, GEPH antibody, HKPX1 antibody, gpgb1 antibody, DKFZp459M0825 antibody, gephyrin antibody, gephyrin L homeolog antibody, gephyrin a antibody, Gphn antibody, GPHN antibody, gphn.L antibody, gphna antibody, PTRG_08978 antibody, VDBG_00775 antibody, Tsp_03043 antibody, gphn antibody

Background: Gephyrin is a microtubule-associated protein highly expressed in brain and localized to neuronal postsynaptic membranes. Gephyrin is essential for the postsynaptic localization of the inhibitory glycine receptor and is thought to anchor the receptor to subsynaptic microtubules. The protein is expressed in most mammalian tissues with predominant expression in brain. At least five additional splice variants of Gephyrin ranging in molecular weight have been identified in rat and human brain tissue.

NCBI Accession: NP_074056

UniProt: Q03555

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development