GBA antibody

Catalog No. ABIN7267407

This anti-GBA antibody is a Rabbit Monoclonal antibody detecting GBA in WB and IHC. Suitable for Human.

Quick Overview for GBA antibody (ABIN7267407)

Target: GBA (Glucosidase, Beta, Acid (GBA))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GBA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GBA Antibody

Purpose: Glucosylceramidase beta (GBA) Rabbit mAb

Cross-Reactivity: Human, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Glucosylceramidase beta (Glucosylceramidase beta (GBA))

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GBA

Target: GBA (Glucosidase, Beta, Acid (GBA))

Alternative Name: GBA

Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010],GBA,GBA1,GCB,GLUC,Cancer,Cell Type Marker,Cell Type Marker_Oligodendrocyte marker,Endocrine & Metabolism,Lipid Metabolism,Neurodegenerative Diseases,Neurodegenerative Diseases_Dopamine Signaling in Parkinsons Disease,Neuroscience,Signal Transduction,GBA

Molecular Weight: 60kDa

Gene ID: 2629

UniProt: P04062

Pathways: Cellular Glucan Metabolic Process