GUCY2F antibody (AA 250-460)

Catalog No. ABIN7267553

The Rabbit Polyclonal anti-GUCY2F antibody has been validated for WB and IF. It is suitable to detect GUCY2F in samples from Human.

Quick Overview for GUCY2F antibody (AA 250-460) (ABIN7267553)

Target: GUCY2F (Guanylate Cyclase 2F, Retinal (GUCY2F))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCY2F antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-GUCY2F Antibody

Binding Specificity: AA 250-460

Purpose: GUCY2F Rabbit pAb

Sequence: HSALIGGETQ MHLLECAHDL KMTDGTYVFV PYDALLYSLP YKHTPYRVLR NNPKLREAYD AVLTITVESQ EKTFYQAFTE AAARGEIPEK LEFDQVSPLF GTIYNSIYFI AQAMNNAMKE NGQAGAASLV QHSRNMQFHG FNQLMRTDSN GNGISEYVIL DTNLKEWELH STYTVDMEME LLRFGGTPIH FPGGRPPRAD AKCWFAEGKI C

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-460 of human GUCY2F (NP_001513.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GUCY2F

Target: GUCY2F (Guanylate Cyclase 2F, Retinal (GUCY2F))

Alternative Name: GUCY2F

Background: The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa.,GUCY2F,CYGF,GC-F,GUC2DL,GUC2F,RETGC-2,ROS-GC2,Signal Transduction,GUCY2F

Molecular Weight: 124kDa

Gene ID: 2986

UniProt: P51841

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction