HFE antibody

Catalog No. ABIN7267606

This Rabbit Monoclonal antibody specifically detects HFE in WB. It exhibits reactivity toward Human.

Quick Overview for HFE antibody (ABIN7267606)

Target: HFE (Hemochromatosis (HFE))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HFE antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HFE Antibody

Purpose: HFE Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human HFE.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HFE

Target: HFE (Hemochromatosis (HFE))

Alternative Name: HFE

Background: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.,HFE, HFE1, HH, HLA-H, MVCD7, TFQTL2, hemochromatosis,Signal Transduction,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases Markers,Other Neurological disorders,Stem Cells,Hematopoietic Progenitors,Amyotrophic lateral sclerosis-ALS,HFE

Molecular Weight: 40kDa

Gene ID: 3077

UniProt: Q30201

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process