PLA2G16 antibody (AA 68-162)

Catalog No. ABIN7267786

This Rabbit Polyclonal antibody specifically detects PLA2G16 in WB. It exhibits reactivity toward Human.

Quick Overview for PLA2G16 antibody (AA 68-162) (ABIN7267786)

Target: PLA2G16 (HRAS-Like Suppressor 3 (PLA2G16))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G16 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLA2G16 Antibody

Binding Specificity: AA 68-162

Purpose: PLA2G16 Rabbit pAb

Sequence: VAGSDKYQVN NKHDDKYSPL PCSKIIQRAE ELVGQEVLYK LTSENCEHFV NELRYGVARS DQVRDVIIAA SVAGMGLAAM SLIGVMFSRN KRQKQ

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 68-162 of human PLA2G16 (NP_009000.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLA2G16

Target: PLA2G16 (HRAS-Like Suppressor 3 (PLA2G16))

Alternative Name: PLA2G16

Background: Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1 and A2 (PLA2 activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O-acyltransferase activity,catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE, forming N-acylphosphatidylethanolamine (NAPE, which serves as precursor for N-acylethanolamines (NAEs. Exhibits high N-acyltransferase activity and low phospholipase A1/2 activity. Required for complete organelle rupture and degradation that occur during eye lens terminal differentiation, when fiber cells that compose the lens degrade all membrane-bound organelles in order to provide lens with transparency to allow the passage of light. Organelle membrane degradation is probably catalyzed by the phospholipase activity (By similarity.,PLA2G16,AdPLA,H-REV107,H-REV107-1,HRASLS3,HREV107,HREV107-1,HREV107-3,HRSL3,Cancer,Tumor suppressors,PLA2G16

Molecular Weight: 18kDa

Gene ID: 11145

UniProt: P53816

Pathways: Inositol Metabolic Process