PLA2G16 antibody

Catalog No. ABIN7254529

The Rabbit Polyclonal anti-PLA2G16 antibody (ABIN7254529) specifically detects PLA2G16 in ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PLA2G16 antibody (ABIN7254529)

Target: PLA2G16 (HRAS-Like Suppressor 3 (PLA2G16))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G16 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-PLA2G16 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human PLA2G16

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLA2G16

Target: PLA2G16 (HRAS-Like Suppressor 3 (PLA2G16))

Alternative Name: PLA2G16

Background: Secretory phopholipase A2 (PLA2) enzymes cleave an acyl ester bond in the sn-2 position of glycerophospholipids. These extracellular proteins have a high disulfide bond content, low molecular mass (14 kDa), and require mM levels of Ca2+ for catalysis. They play a crucial role in the generation of arachidonates and eicosanoids, and have a number of biological actions including immunological responses, inflammation, cellular proliferation, vasoconstriction, and bronchioconstriction. Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity). N- and O-acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity.

UniProt: P53816

Pathways: Inositol Metabolic Process