IGKC antibody

Catalog No. ABIN7267846

This Rabbit Monoclonal antibody specifically detects IGKC in WB. It exhibits reactivity toward Human.

Quick Overview for IGKC antibody (ABIN7267846)

Target: IGKC (Immunoglobulin kappa Constant (IGKC))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IGKC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IGKC Antibody

Purpose: Human Ig Kappa Chain Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Human Ig Kappa Chain

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IGKC

Target: IGKC (Immunoglobulin kappa Constant (IGKC))

Alternative Name: IGKC

Background: Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.,HCAK1, IGKCD, Km,Immunology & Inflammation,IGKC

Molecular Weight: 26kDa

Gene ID: 3514

UniProt: P01834