Importin 8 antibody (AA 878-1037)

Catalog No. ABIN7267859

The Rabbit Polyclonal anti-Importin 8 antibody has been validated for WB and IF. It is suitable to detect Importin 8 in samples from Human.

Quick Overview for Importin 8 antibody (AA 878-1037) (ABIN7267859)

Target: Importin 8 (IPO8)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Importin 8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Importin 8 Antibody

Binding Specificity: AA 878-1037

Purpose: IPO8 Rabbit pAb

Sequence: TRQLVNREDR SKAEKADMEE NEEISSDEEE TNVTAQAMQS NNGRGEDEEE EDDDWDEEVL EETALEGFST PLDLDNSVDE YQFFTQALIT VQSRDAAWYQ LLMAPLSEDQ RTALQEVYTL AEHRRTVAEA KKKIEQQGGF TFENKGVLSA FNFGTVPSNN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 878-1037 of human IPO8 (NP_006381.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Importin 8

Target: Importin 8 (IPO8)

Alternative Name: IPO8

Background: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,IPO8,RANBP8,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,IPO8

Molecular Weight: 96kDa/119kDa

Gene ID: 10526

UniProt: O15397