ITGAL antibody

Catalog No. ABIN7267923

The Rabbit Monoclonal anti-ITGAL antibody (ABIN7267923) specifically detects ITGAL in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for ITGAL antibody (ABIN7267923)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ITGAL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ITGAL Antibody

Purpose: CD11a/LFA-1A/ITGAL Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human CD11a/LFA-1A/ITGAL

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: ITGAL

Background: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],CD11A,LFA-1,LFA1A,CD11a,ITGAL,CDs,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Hematopoietic Progenitors,Immunology & Inflammation,MAPK-Erk Signaling Pathway,PI3K-Akt Signaling Pathway,Signal Transduction,Stem Cells,T Cell Receptor Signaling Pathway,ITGAL

Molecular Weight: 180kDa

Gene ID: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex