KBTBD8 antibody

Catalog No. ABIN7268076

This anti-KBTBD8 antibody is a Rabbit Polyclonal antibody detecting KBTBD8 in WB and IF. Suitable for Human.

Quick Overview for KBTBD8 antibody (ABIN7268076)

Target: KBTBD8 (Kelch Repeat and BTB (POZ) Domain Containing 8 (KBTBD8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KBTBD8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-KBTBD8 Antibody

Purpose: KBTBD8 Rabbit pAb

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human KBTBD8.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KBTBD8

Target: KBTBD8 (Kelch Repeat and BTB (POZ) Domain Containing 8 (KBTBD8))

Alternative Name: KBTBD8

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1 E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8 complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.,TA-KRP,TAKRP,KBTBD8,Cell Biology & Developmental Biology,KBTBD8

Gene ID: 84541

UniProt: Q8NFY9