KIF20B antibody (AA 1200-1500)

Catalog No. ABIN7268126

The Rabbit Polyclonal anti-KIF20B antibody has been validated for WB and IF. It is suitable to detect KIF20B in samples from Human.

Quick Overview for KIF20B antibody (AA 1200-1500) (ABIN7268126)

Target: KIF20B (Kinesin Family Member 20B (KIF20B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF20B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-KIF20B Antibody

Binding Specificity: AA 1200-1500

Purpose: KIF20B Rabbit pAb

Sequence: KHLLQLKEEE EETNRQETEK LKEELSASSA RTQNLKADLQ RKEEDYADLK EKLTDAKKQI KQVQKEVSVM RDEDKLLRIK INELEKKKNQ CSQELDMKQR TIQQLKEQLN NQKVEEAIQQ YERACKDLNV KEKIIEDMRM TLEEQEQTQV EQDQVLEAKL EEVERLATEL EKWKEKCNDL ETKNNQRSNK EHENNTDVLG KLTNLQDELQ ESEQKYNADR KKWLEEKMML ITQAKEAENI RNKEMKKYAE DRERFFKQQN EMEILTAQLT EKDSDLQKWR EERDQLVAAL EIQLKALISS N

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1500 of human KIF20B (NP_057279.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KIF20B

Target: KIF20B (Kinesin Family Member 20B (KIF20B))

Alternative Name: KIF20B

Background: Plus-end-directed motor enzyme that is required for completion of cytokinesis. Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression.,KIF20B,CT90,KRMP1,MPHOSPH1,MPP-1,MPP1,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cytoskeleton,Motor Proteins,KIF20B

Molecular Weight: 59kDa/199kDa/206kDa/210kDa/214kDa

Gene ID: 9585

UniProt: Q96Q89

Pathways: M Phase