Klotho beta antibody (AA 720-990)

Catalog No. ABIN7268146

This Rabbit Polyclonal antibody specifically detects Klotho beta in WB. It exhibits reactivity toward Human.

Quick Overview for Klotho beta antibody (AA 720-990) (ABIN7268146)

Target: Klotho beta (KLB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Klotho beta antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Klotho beta Antibody

Binding Specificity: AA 720-990

Purpose: KLB Rabbit pAb

Sequence: ALAWRLYDRQ FRPSQRGAVS LSLHADWAEP ANPYADSHWR AAERFLQFEI AWFAEPLFKT GDYPAAMREY IASKHRRGLS SSALPRLTEA ERRLLKGTVD FCALNHFTTR FVMHEQLAGS RYDSDRDIQF LQDITRLSSP TRLAVIPWGV RKLLRWVRRN YGDMDIYITA SGIDDQALED DRLRKYYLGK YLQEVLKAYL IDKVRIKGYY AFKLAEEKSK PRFGFFTSDF KAKSSIQFYN KVISSRGFPF ENSSSRCSQT QENTECTVCL F

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 720-990 of human KLB (NP_783864.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Klotho beta

Target: Klotho beta (KLB)

Alternative Name: KLB

Background: Klotho is an anti-aging single-pass membrane protein predominantly produced in the kidney, with shedding of the amino-terminal extracellular domain into the systemic circulation. Circulating levels of soluble Klotho decrease with age, and the klotho gene is associated with increased risk of age-related diseases.,KLB,BKL,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Lipids,KLB

Molecular Weight: 119kDa

Gene ID: 152831

UniProt: Q86Z14

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding