Klotho beta antibody (AA 1-29)

Catalog No. ABIN6242210

Product Details anti-Klotho beta Antibody

Target: Klotho beta (KLB)

Binding Specificity: AA 1-29

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Klotho beta antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KLB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from human KLB.

Clone: RB55007

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for Klotho beta

Target: Klotho beta (KLB)

Alternative Name: KLB (KLB Products)

Synonyms: KLB antibody, BKL antibody, AV071179 antibody, betaKlotho antibody, Klb-ps1 antibody, RGD1308227 antibody, klotho beta antibody, KLB antibody, Klb antibody

Background: Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).

Molecular Weight: 119808

UniProt: Q86Z14

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding