LGR5 antibody

Catalog No. ABIN7268230

This Rabbit Monoclonal antibody specifically detects LGR5 in WB. It exhibits reactivity toward Human.

Quick Overview for LGR5 antibody (ABIN7268230)

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This LGR5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LGR5 Antibody

Purpose: LGR5/GPR49 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human LGR5/GPR49

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LGR5

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Alternative Name: LGR5

Background: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015],FEX, GPR49, GPR67, GRP49, HG38,Cancer,G protein signaling,G protein signaling_G-Protein-Coupled Receptors(GPCR),Signal Transduction,Stem Cells,LGR5

Molecular Weight: 100kDa

Gene ID: 8549

UniProt: O75473

Pathways: WNT Signaling