LTC4S antibody (C-Term)

Catalog No. ABIN7268248

This Rabbit Polyclonal antibody specifically detects LTC4S in WB. It exhibits reactivity toward Human.

Quick Overview for LTC4S antibody (C-Term) (ABIN7268248)

Target: LTC4S (Leukotriene C4 Synthase (LTC4S))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTC4S antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LTC4S Antibody

Binding Specificity: C-Term

Purpose: LTC4S Rabbit pAb

Sequence: YRAQVNCSEY FPLFLATLWV AGIFFHEGAA ALCGLVYLFA RLRYFQGYAR SAQLRLAPLY ASARALWLLV ALAALGLLAH FLPAALRAAL LGRLRTLLPW A

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human LTC4S (NP_665874.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LTC4S

Target: LTC4S (Leukotriene C4 Synthase (LTC4S))

Alternative Name: LTC4S

Background: The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum.,LTC4S,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,LTC4S

Molecular Weight: 16kDa

Gene ID: 4056

UniProt: Q16873

Pathways: Cellular Response to Molecule of Bacterial Origin