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LTC4S antibody (N-Term)

LTC4S Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rat, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783616
  • Target See all LTC4S Antibodies
    LTC4S (Leukotriene C4 Synthase (LTC4S))
    Binding Specificity
    • 10
    • 7
    • 4
    • 1
    N-Term
    Reactivity
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rat, Rabbit, Zebrafish (Danio rerio)
    Host
    • 22
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    This LTC4S antibody is un-conjugated
    Application
    • 17
    • 16
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MKDEVALLAA VTLLGVLLQA YFSLQVISAR RAFRVSPPLT TGPPEFERVY
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 92%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against LTC4S. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human LTC4S
    Top Product
    Discover our top product LTC4S Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 150 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tang, Sally, Lesko, Discepolo, Abadie, Ciszewski, Semrad, Guandalini, Kupfer, Jabri: "Cysteinyl leukotrienes mediate lymphokine killer activity induced by NKG2D and IL-15 in cytotoxic T cells during celiac disease." in: The Journal of experimental medicine, Vol. 212, Issue 10, pp. 1487-95, (2015) (PubMed).

  • Target
    LTC4S (Leukotriene C4 Synthase (LTC4S))
    Alternative Name
    LTC4S (leukotriene C4 synthase) (LTC4S) (LTC4S Products)
    Synonyms
    LTC4S antibody, ltc4s antibody, si:dkey-33h4.2 antibody, leukotriene C4 synthase antibody, leukotriene C4 synthase-like antibody, leukotriene C4 synthase, gene 1 antibody, Ltc4s antibody, LTC4S antibody, LTC4SL antibody, ltc4s.1 antibody, ltc4s antibody
    Background
    The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. LTC4S is an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma.The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC33147
    Protein Interaction Partner: MGST1, LTC4S, ALOX5AP, ALOX5,
    Protein Size: 150
    Molecular Weight
    16 kDa
    Gene ID
    4056
    NCBI Accession
    NM_145867, NP_665874
    UniProt
    Q16873
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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