KDM2B antibody (AA 600-700)

Catalog No. ABIN7268327

The Rabbit Polyclonal anti-KDM2B antibody has been validated for WB. It is suitable to detect KDM2B in samples from Human.

Quick Overview for KDM2B antibody (AA 600-700) (ABIN7268327)

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KDM2B Antibody

Binding Specificity: AA 600-700

Purpose: KDM2B Rabbit pAb

Sequence: SGCSWIAVSA LCSSSCPLLR TLDVQWVEGL KDAQMRDLLS PPTDNRPGQM DNRSKLRNIV ELRLAGLDIT DASLRLIIRH MPLLSKLHLS YCNHVTDQSI N

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 600-700 of human KDM2B (XP_011537177.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KDM2B

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Alternative Name: KDM2B

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.,KDM2B,CXXC2,FBXL10,Fbl10,JHDM1B,PCCX2,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Demethylation,KDM2B

Molecular Weight: 63kDa/144kDa/149kDa/151kDa/152kDa

Gene ID: 84678

UniProt: Q8NHM5

Pathways: Tube Formation, Warburg Effect