MXD3 antibody
Quick Overview for MXD3 antibody (ABIN7268429)
Target
See all MXD3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- MAD3/MXD3 Rabbit mAb
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human MAD3/MXD3
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- MXD3 (MAX Dimerization Protein 3 (MXD3))
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Alternative Name
- MXD3
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Background
- This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008],BHLHC13, MAD3, MYX,Cancer,Epigenetics & Nuclear Signaling,Transcription Factors,Tumor suppressors,MXD3
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Molecular Weight
- 28kDa
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Gene ID
- 83463
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UniProt
- Q9BW11
Target
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