MKKS antibody (AA 221-570)

Catalog No. ABIN7268433

This anti-MKKS antibody is a Rabbit Polyclonal antibody detecting MKKS in WB. Suitable for Human.

Quick Overview for MKKS antibody (AA 221-570) (ABIN7268433)

Target: MKKS (McKusick-Kaufman Syndrome (MKKS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKKS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MKKS Antibody

Binding Specificity: AA 221-570

Purpose: MKKS Rabbit pAb

Sequence: EMSEVQLMRL LPIKKSTALK VALFCTTLSG DTSDTGEGTV VVSYGVSLEN AVLDQLLNLG RQLISDHVDL VLCQKVIHPS LKQFLNMHRI IAIDRIGVTL MEPLTKMTGT QPIGSLGSIC PNSYGSVKDV CTAKFGSKHF FHLIPNEATI CSLLLCNRND TAWDELKLTC QTALHVLQLT LKEPWALLGG GCTETHLAAY IRHKTHNDPE SILKDDECTQ TELQLIAEAF CSALESVVGS LEHDGGEILT DMKYGHLWSV QADSPCVANW PDLLSQCGCG LYNSQEELNW SFLRSTRRPF VPQSCLPHEA VGSASNLTLD CLTAKLSGLQ VAVETANLIL DLSYVIEDKN

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 221-570 of human MKKS (NP_740754.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MKKS

Target: MKKS (McKusick-Kaufman Syndrome (MKKS))

Alternative Name: MKKS

Background: This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants.,MKKS,BBS6,HMCS,KMS,MKS,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Immunology & Inflammation,Cytokines,MKKS

Molecular Weight: 62kDa

Gene ID: 8195

UniProt: Q9NPJ1

Pathways: Sensory Perception of Sound