MED20 antibody (AA 1-212)

Catalog No. ABIN7268441

The Rabbit Polyclonal anti-MED20 antibody has been validated for WB. It is suitable to detect MED20 in samples from Human.

Quick Overview for MED20 antibody (AA 1-212) (ABIN7268441)

Target: MED20 (Mediator Complex Subunit 20 (MED20))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED20 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MED20 Antibody

Binding Specificity: AA 1-212

Purpose: MED20 Rabbit pAb

Sequence: MGVTCVSQMP VAEGKSVQQT VELLTRKLEM LGAEKQGTFC VDCETYHTAA STLGSQGQTG KLMYVMHNSE YPLSCFALFE NGPCLIADTN FDVLMVKLKG FFQSAKASKI ETRGTRYQYC DFLVKVGTVT MGPSARGISV EVEYGPCVVA SDCWSLLLEF LQSFLGSHTP GAPAVFGNRH DAVYGPADTM VQYMELFNKI RKQQQVPVAG IR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human MED20 (NP_004266.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MED20

Target: MED20 (Mediator Complex Subunit 20 (MED20))

Alternative Name: MED20

Background: This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. A mutation in this gene has been associated with a novel infantile-onset neurodegenerative movement disorder. Alternatively spliced transcript variants have been identified.,MED20,PRO0213,TRFP,SRB2,Epigenetics & Nuclear Signaling,MED20

Molecular Weight: 13kDa/23kDa

Gene ID: 9477

UniProt: Q9H944

Pathways: Regulation of Lipid Metabolism by PPARalpha