LC3B antibody (AA 1-125)

Catalog No. ABIN7268518

This Rabbit Polyclonal antibody specifically detects LC3B in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for LC3B antibody (AA 1-125) (ABIN7268518)

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LC3B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LC3B Antibody

Binding Specificity: AA 1-125

Purpose: LC3A / LC3B Rabbit pAb

Sequence: MPSEKTFKQR RTFEQRVEDV RLIREQHPTK IPVIIERYKG EKQLPVLDKT KFLVPDHVNM SELIKIIRRR LQLNANQAFF LLVNGHSMVS VSTPISEVYE SEKDEDGFLY MVYASQETFG MKLSV

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human LC3A / LC3B (NP_073729.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LC3B

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Alternative Name: MAP1LC3A/MAP1LC3B

Background: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.,MAP1LC3B,ATG8F,LC3B,MAP1A/1BLC3,MAP1LC3B-a,MAP1LC3A,ATG8E,LC3,LC3A,MAP1ALC3,MAP1BLC3,LC3A/LC3B,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Cytoskeleton,Microtubules,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Cardiovascular,Heart,ATGs,MAP1LC3A/MAP1LC3B

Molecular Weight: 14kDa

Gene ID: 84557, 81631

UniProt: Q9GZQ8, Q9H492

Pathways: Autophagy