Myoferlin antibody (AA 1-190)

Catalog No. ABIN7268735

The Rabbit Polyclonal anti-Myoferlin antibody has been validated for WB. It is suitable to detect Myoferlin in samples from Human.

Quick Overview for Myoferlin antibody (AA 1-190) (ABIN7268735)

Target: Myoferlin (MYOF)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myoferlin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Myoferlin Antibody

Binding Specificity: AA 1-190

Purpose: MYOF Rabbit pAb

Sequence: MLRVIVESAS NIPKTKFGKP DPIVSVIFKD EKKKTKKVDN ELNPVWNEIL EFDLRGIPLD FSSSLGIIVK DFETIGQNKL IGTATVALKD LTGDQSRSLP YKLISLLNEK GQDTGATIDL VIGYDPPSAP HPNDLSGPSV PGMGGDGEED EGDEDRLDNA VRGPGPKGPV GTVSEAQLAR RLTKVKNSRR

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MYOF (NP_038479.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Myoferlin

Target: Myoferlin (MYOF)

Alternative Name: MYOF

Background: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.,MYOF,FER1L3,myoferlin,Cell Biology & Developmental Biology,Cardiovascular,MYOF

Molecular Weight: 17kDa/46kDa/49kDa/179kDa/229kDa/233kDa/234kDa

Gene ID: 26509

UniProt: Q9NZM1