MYH7 antibody

Catalog No. ABIN7268750

The Rabbit Monoclonal anti-MYH7 antibody has been validated for WB, IHC and IF. It is suitable to detect MYH7 in samples from Human.

Quick Overview for MYH7 antibody (ABIN7268750)

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MYH7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MYH7 Antibody

Purpose: Myosin heavy chain Rabbit mAb

Cross-Reactivity: Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Myosin heavy chain

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MYH7

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Alternative Name: MYH7

Background: Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008],CMD1S, CMH1, MPD1, MYHCB, SPMD, SPMM,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Motor Proteins,Signal Transduction,MYH7

Molecular Weight: 224kDa

Gene ID: 4625, 4624

UniProt: P12883, P13533