MYST3 antibody (AA 800-1000)

Catalog No. ABIN7268768

The Rabbit Polyclonal anti-MYST3 antibody has been validated for WB, IHC and IF. It is suitable to detect MYST3 in samples from Human.

Quick Overview for MYST3 antibody (AA 800-1000) (ABIN7268768)

Target: MYST3 (MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYST3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MYST3 Antibody

Binding Specificity: AA 800-1000

Purpose: KAT6A Rabbit pAb

Sequence: EEPQCQEREL EISVGKSVSH ENKEQDSYSV ESEKKPEVMA PVSSTRLSKQ VLPHDSLPAN SQPSRRGRWG RKNRKTQERF GDKDSKLLLE ETSSAPQEQY GECGEKSEAT QEQYTESEEQ LVASEEQPSQ DGKPDLPKRR LSEGVEPWRG QLKKSPEALK CRLTEGSERL PRRYSEGDRA VLRGFSESSE EEEEPESPRS S

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 800-1000 of human KAT6A (NP_001092883.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MYST3

Target: MYST3 (MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3))

Alternative Name: KAT6A

Background: This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with autosomal dominant mental retardation-32. Alternative splicing results in multiple transcript variants.,KAT6A,MOZ,MRD32,MYST-3,MYST3,RUNXBP2,ZC2HC6A,ZNF220,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Acetylation,KAT6A

Molecular Weight: 225kDa

Gene ID: 7994

UniProt: Q92794

Pathways: Stem Cell Maintenance, Embryonic Body Morphogenesis