MYST3 antibody (C-Term)

Catalog No. ABIN127315

This Rabbit Polyclonal antibody specifically detects MYST3 in WB. It exhibits reactivity toward Human.

Quick Overview for MYST3 antibody (C-Term) (ABIN127315)

Target: MYST3 (MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYST3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MYST3 Antibody

Binding Specificity: C-Term

Specificity: The antibody recognizes 220 kDa HAT-3. A 50 kDa unknown band can also be detected.

Purification: Affinity chromatography on Protein A

Immunogen: Synthetic peptide containing amino acids near the C-terminus of the human HAT-3

Application Details

Application Notes: Western blot: 2 - 6 μg/mL. Jurkat cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered saline (PBS) containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody at -20 °C to -70 °C.

Target Details for MYST3

Target: MYST3 (MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3))

Alternative Name: MYST3

Background: Histone acetyltransferases (HATs) have been implicated in a number of cellular functions including gene regulation, DNA synthesis, and repair. Histone acetyltransferases and deacetylases are respectively, the enzymes devoted to thr addition and removal of acetyl groups from lysine residues on the Histone N-terminal trails. The enzymes exert fundamental roles in developmental processes and their deregulation has been linked to the progression of diverse human disorders, including cancer.Synonyms: Histone acetyltransferase MYST3, MOZ, Monocytic leukemia zinc finger protein, RUNXBP2, Runt-related transcription factor-binding protein 2, SAS2 and TIP60 protein 3, YBF2/SAS3, ZNF220, Zinc finger protein 220

Gene ID: 7994

NCBI Accession: NP_001092882

UniProt: Q92794

Pathways: Stem Cell Maintenance, Embryonic Body Morphogenesis