N-Glycanase 1 antibody (AA 1-300)

Catalog No. ABIN7268780

The Rabbit Polyclonal anti-N-Glycanase 1 antibody has been validated for WB. It is suitable to detect N-Glycanase 1 in samples from Human.

Quick Overview for N-Glycanase 1 antibody (AA 1-300) (ABIN7268780)

Target: N-Glycanase 1 (NGLY1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This N-Glycanase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-N-Glycanase 1 Antibody

Binding Specificity: AA 1-300

Purpose: NGLY1 Rabbit pAb

Sequence: MAAAALGSSS GSASPAVAEL CQNTPETFLE ASKLLLTYAD NILRNPNDEK YRSIRIGNTA FSTRLLPVRG AVECLFEMGF EEGETHLIFP KKASVEQLQK IRDLIAIERS SRLDGSNKSH KVKSSQQPAA STQLPTTPSS NPSGLNQHTR NRQGQSSDPP SASTVAADSA ILEVLQSNIQ HVLVYENPAL QEKALACIPV QELKRKSQEK LSRARKLDKG INISDEDFLL LELLHWFKEE FFHWVNNVLC SKCGGQTRSR DRSLLPSDDE LKWGAKEVED HYCDACQFSN RFPRYNNPEK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NGLY1 (NP_060767.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for N-Glycanase 1

Target: N-Glycanase 1 (NGLY1)

Alternative Name: NGLY1

Background: This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role in the proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.,NGLY1,CDDG,CDG1V,PNG1,PNGase,Cell Biology & Developmental Biology,Ubiquitin,NGLY1

Molecular Weight: 14kDa/63kDa/70kDa/72kDa/74kDa

Gene ID: 55768

UniProt: Q96IV0

Pathways: Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome