NDRG1 antibody

Catalog No. ABIN7268783

The Rabbit Monoclonal anti-NDRG1 antibody has been validated for WB and IHC. It is suitable to detect NDRG1 in samples from Human.

Quick Overview for NDRG1 antibody (ABIN7268783)

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NDRG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NDRG1 Antibody

Purpose: NDRG1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human NDRG1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NDRG1

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Alternative Name: NDRG1

Background: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5,Angiogenesis,Cancer,Cardiovascular,Epigenetics & Nuclear Signaling,Invasion and Metastasis,Neurodegenerative Diseases,Neuroscience,Protein phosphorylation,Signal Transduction,NDRG1

Molecular Weight: 43kDa

Gene ID: 10397

UniProt: Q92597