NEFH antibody

Catalog No. ABIN7268866

This Rabbit Monoclonal antibody specifically detects NEFH in WB, IHC, IF and IP. It exhibits reactivity toward Human.

Quick Overview for NEFH antibody (ABIN7268866)

Target: NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NEFH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-NEFH Antibody

Purpose: Neurofilament H Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Neurofilament H

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NEFH

Target: NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Alternative Name: NEFH

Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008],CMT2CC,NFH,NEFH,Cell Adhesion,Cell Biology & Developmental Biology,Cell Type Marker,Cell Type Marker_Axon marker,Cell Type Marker_Neuron marker,Cytoskeleton,Cytoskeleton_Intermediate Filaments,Neurodegenerative Diseases,Neurodegenerative Diseases_Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neuroscience,Signal Transduction,NEFH

Molecular Weight: 200kDa

Gene ID: 4744

UniProt: P12036