NKIRAS1 antibody (AA 118-192)

Catalog No. ABIN7268903

The Rabbit Polyclonal anti-NKIRAS1 antibody has been validated for WB and IF. It is suitable to detect NKIRAS1 in samples from Human.

Quick Overview for NKIRAS1 antibody (AA 118-192) (ABIN7268903)

Target: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKIRAS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-NKIRAS1 Antibody

Binding Specificity: AA 118-192

Purpose: NKIRAS1 Rabbit pAb

Sequence: LGNKIDLSEQ RQVDAEVAQQ WAKSEKVRLW EVTVTDRKTL IEPFTLLASK LSQPQSKSSF PLPGRKNKGN SNSEN

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 118-192 of human NKIRAS1 (NP_065078.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NKIRAS1

Target: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Alternative Name: NKIRAS1

Background: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.,NKIRAS1,KBRAS1,kappaB-Ras1,Signal Transduction,NKIRAS1

Molecular Weight: 21kDa

Gene ID: 28512

UniProt: Q9NYS0