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ENOS antibody (AA 680-780)
The Rabbit Polyclonal anti-ENOS antibody has been validated for WB, IHC and IF. It is suitable to detect ENOS in samples from Human.
Quick Overview for ENOS antibody (AA 680-780) (ABIN7268921)
Target
See all ENOS (NOS3) Antibodies
ENOS (NOS3)
(Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))
Reactivity
All reactivities for ENOS antibodies
Human
Host
All hosts for ENOS antibodies
Rabbit
Clonality
All clonalities for ENOS antibodies
Polyclonal
Conjugate
All conjugates for ENOS antibodies
This ENOS antibody is un-conjugated
Application
All applications for ENOS antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Product Details anti-ENOS Antibody
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Binding Specificity
All epitopes for ENOS antibodies
AA 680-780
Purpose
eNOS Rabbit pAb
Sequence
LQLGQGDELC GQEEAFRGWA QAAFQAACET FCVGEDAKAA ARDIFSPKRS WKRQRYRLSA QAEGLQLLPG LIHVHRRKMF QATIRSVENL QSSKSTRATI L
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 680-780 of human eNOS (NP_000594.2).
Isotype
IgG
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for ENOS
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Target
ENOS (NOS3)
(Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))
Alternative Name
NOS3
Background
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants.,NOS3,ECNOS,eNOS,Cancer,Signal Transduction,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Endocrine & Metabolism,AMPK Signaling Pathway,Neuroscience,Cardiovascular,Angiogenesis,Blood,Hypoxia,NOS3
Molecular Weight
67kDa/68kDa/133kDa
Gene ID
4846
UniProt
P29474
Pathways
ACE Inhibitor Pathway , Regulation of Systemic Arterial Blood Pressure by Hormones , Cellular Response to Molecule of Bacterial Origin , Myometrial Relaxation and Contraction , Signaling Events mediated by VEGFR1 and VEGFR2 , Thromboxane A2 Receptor Signaling , VEGFR1 Specific Signals , VEGF Signaling
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